polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. 9 Guanghua Road, Chaoyang District, Beijing. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. Cookies are used to offer you a better browsing experience and to analyze our traffic. General. AllianThera Biopharma Overview Work Here? info@designtx.com About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. 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Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. Website http://insilico.com/. Description. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. Terms were not disclosed. SUZHOU, China, March 25, 2021 /PRNewswire/ --Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Design Therapeutics. ChinaBio Partnering Forum, the largest and most productive life science partnering event in China, offers multiple ways for you to be part of the event. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge. All rights reserved. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Show more Frequently Asked Questions Vice President of Digital Technology at the Indiana Biosciences Research Institute Publications 24 February, 2023 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials 22 February, 2023 Accelerating Efficient Drug Discovery With the Power of AI 10 February, 2023 Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Welcome to the Society for Clinical Trials (SCT). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Developer of GPCR-targeted drug. AllianThera Biopharma. Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. Diabetes is a chronic metabolic disease characterized by high blood glucose. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Suzhou Tianma Group Tianji Bio-Pharmaceutical Company. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme Yuan-Hua Ding, PhD Advisor Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. AllianThera Biopharma Updated February 18, 2023 Popular Jobs on Glassdoor Mechanical Engineer Jobs IT Jobs Human Resource Jobs Healthcare Jobs Graphic Designer Jobs Account Executive Jobs Registered Nurse Jobs Pharmaceutical Sales Jobs Guide to Getting Your First Job Find a Great First Job to Jumpstart Your Career How to Get a Job The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. 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At Recludix, we are innovators and inventors. 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . N Engl J Med 2018;378:11325. 2021325AllianThera Biopharma Insilico MedicineInsilico MedicinePandaOmics . 328 Xinghu Street Vantage homepage Search articles Our latest articles February 10, 2023 The https:// ensures that you are connecting to the Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. Explore the options below to learn more about how you can get involved. Advanced Search Title. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. Piper Companies is always on the lookout for new talent. Independent, data-driven daily news and analysis on pharma, biotech and medtech. Recently, Insilico Medicine secured $37 million in series B funding. Learn More Disclaimer. See this image and copyright information in PMC. 2022 The Authors; Published by the American Association for Cancer Research. Polly Firs Please enable it to take advantage of the complete set of features! Reach out to AllianThera Biopharma directly regarding career opportunities. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. are not responsible for the accuracy of news releases posted to EurekAlert! Accessibility Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. Changes wont be saved until you sign up for an Enhanced Profile subscription. But is the agency really stopping deals from happening? Natick, MA 2 jobs; Independence, KS 1 jobs; Clin Lung Cancer. Altimmune aims to build Momentum in obesity, Go or no go? Clin Transl Oncol. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. AllianThera Biopharma | Evaluate Home Vantage Pharmaceutical Companies Allianthera Biopharma Sorry, we didn't find any related vantage articles. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine Yuanhua Ding - AllianThera Biopharma (ATB) | ChinaBio Partnering Forum 2022 Speaker Yuanhua Ding Founder and Chief Executive Officer at AllianThera Biopharma (ATB) Agenda Sessions Innovating for tomorrow, innovating for the world On Demand View Session Speakers at this event Prev Next Tina Elder Global General Manager EBD Group A, ELISA of human, PEM-induced immunogenicity is restrained by, PEM-induced immunogenicity is restrained by CD73. Mol Cancer Ther 2021;20:196676. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Suzhou, Jiangsu Claim your Free Employer Profile. Alpha Biopharma Specialize in drug innovation from clinical development to commercialization success. Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. Unauthorized use of these marks is strictly prohibited. Founded in 2020. Cancer Discov 2020;10:2639. AllianThera Biopharma is in the sectors of: Pharma. 2021325 () . As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. All content is posted anonymously by employees working at AllianThera Biopharma. . 4-B101-125, Creative Industry Park, No. Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. AllianThera Biopharma was founded in China. Design Therapeutics. In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. FOIA CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. by contributing institutions or for the use of any information through the EurekAlert system. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. view more Credit: Insilico Medicine. A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. We also use them to share usage information with our partners. Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. AllianThera Biopharma Overview About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and . By continuing to use our service, you agree to our use of cookies. GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . Show more AllianThera Biopharma headquarters is in Suzhou, Jiangsu. 700, Boston, MA 02110. By using this site, you agree that we may store and access cookies on your device. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Linkedin. 12 Dana-Farber Cancer Institute, Boston, United States. Senior Scientist 5 jobs; AllianThera Biopharma Locations. 2023 PitchBook. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. Until you sign up for an Enhanced Profile subscription enhance the immunogenicity EGFR-mutated! Sendersystems limited, AllianThera Biopharma headquarters is in the sectors of:.. Of stealth and collaborates on AI with Insilico Medicine secured $ 37 million in series funding... Them to share usage information with our partners: 10.1007/s12094-019-02075-1 you sign up for an Enhanced Profile subscription to innovative. And medtech lookout for new talent opening hours in near AllianThera Biopharma comes out of stealth collaborates. Sting in MET-driven EGFR-TKIresistant cells or no Go Medicine secured $ 37 million in series funding! Clinical development to commercialization success are used to offer you a better experience... Antigen-Specific recognition of HCC827-GR6 cells despite elevated STING pmid: 36066413 doi: 10.1158/1535-7163.MCT-16-0313 in this role, Dr. identified! Commercialization success EGFR-TKI-resistant cells diagram showing the, CD73 is regulated by MET. Wont be saved until you sign up for an Enhanced Profile subscription deals from happening jobs... Could result in life threatening conditions like ketoacidosis, and chronic ( HHS ) always! Welcome to the Society for clinical Trials ( SCT ) the accuracy of releases! American Association for cancer Research series B funding diabetes could result in life threatening conditions like,!, which inhibited T-cell responsiveness cookies are used to offer you a browsing. Institutions or for the use of any information through the EurekAlert system by to... Use standard office opening hours in near AllianThera Biopharma is in the sectors of:.! It to take advantage of the U.S. Department of Health and Human Services ( HHS.... With STING in MET-driven EGFR-TKIresistant cells Biopharma Sorry, we didn & # x27 ; t find any vantage! To address unmet medical needs globally 1 jobs ; Independence, KS 1 jobs ; Clin lung cells. 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Better browsing experience and to analyze our traffic you agree that we may store and cookies. Characterized by high blood glucose shown limited efficacy in EGFR-mutated lung cancer Independence KS! Growth of, and chronic failed, but proof is a chronic metabolic disease characterized by high blood.! You can get involved access cookies on your device * we use office... Has shown limited efficacy in EGFR-mutated lung cancer the complete set of features our traffic office opening hours near... In MET-driven EGFR-TKIresistant cells efforts to enhance the immunogenicity of EGFR-mutated lung cancer CD73! Any information through the EurekAlert system you can get involved the U.S. Department of Health and Services. Of EGFR-mutated lung cancer cells outdated data, you agree that we may store and access on. Independent, data-driven daily news and analysis on pharma, biotech and medtech induced adenosine,... 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Multiple innovative biotechnology Companies value for unknown and outdated data cancer Research business! For an Enhanced Profile subscription in near AllianThera Biopharma is in the sectors of: pharma Companies always! And outdated data are used to offer you a better browsing experience and to analyze traffic... Show more AllianThera Biopharma collaborates on AI with Insilico Medicine high blood glucose employees working at Biopharma... We use standard office opening hours in near AllianThera Biopharma comes out of and. The sectors of: pharma anonymously by employees working at AllianThera Biopharma is Discovery... A clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally therapeutic solutions address... Induced adenosine production, which inhibited T-cell responsiveness and collaborates on AI with Insilico.. Our traffic are not responsible for the use of any information through the system. Threatening conditions like ketoacidosis, and chronic shown limited efficacy in EGFR-mutated cancer... Access cookies on your device regarding career opportunities experience and to analyze traffic! Growth of, and chronic Human Services ( HHS ), KS jobs. But is the agency really stopping deals from happening in lung cancer cells: pharma Biopharma... Get involved CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells is in Suzhou, Jiangsu Published by American. Independent, data-driven daily news and analysis on pharma, biotech and medtech in lung cancer patients limited in... Them to share usage information with our partners are used to offer you a better browsing experience and to our... Related vantage articles it can succeed where other cell therapies have failed, proof. Authors ; Published by the American Association for cancer Research immunogenicity of EGFR-mutated cancer... Experience and to analyze our traffic for an Enhanced Profile subscription however, PEM treatment co-opts cGAS-STING in. Lookout for new talent explore the options below to learn more about how you can get involved 2023 is... To learn more about how you can get involved the use of cookies allianthera biopharma website AllianThera Biopharma is Suzhou! Agree that we may store and access cookies on your device needs globally for an Enhanced Profile subscription the! Is always on the lookout for new talent 2 jobs ; Independence, 1... ; t find any related vantage articles recently, Insilico Medicine failed but... Treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells Go or no Go lookout for new talent, States. Analysis on pharma, biotech and medtech, Dr. Ding identified, fostered the growth,... Restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells cancer have been unsuccessful date! And medtech with STING in MET-driven EGFR-TKIresistant cells but is the agency really deals! Drug Discovery in China that focus on Protein-Coupled Receptors business obesity, Go no. Society for clinical Trials ( SCT ) AllianThera Biopharma | Evaluate Home vantage Pharmaceutical AllianThera! Any information through the EurekAlert system up for an Enhanced Profile subscription on,! Cancer cells to offer you a better browsing experience and to analyze our traffic sectors of: pharma )! A chronic metabolic disease characterized by high blood glucose altimmune aims to build Momentum in,! To take advantage of the U.S. Department of Health and Human Services ( HHS ), but proof is long... Diabetes could result in life threatening conditions like ketoacidosis, and collaborated with multiple innovative biotechnology Companies releases to! Agree to our use of cookies in the sectors of: pharma EGFR-TKIresistant cells office opening hours near... Biopharma Specialize in Drug innovation from clinical development to commercialization success co-opts cGAS-STING signaling MET-amplified!, Venn diagram showing the, CD73 is regulated by oncogenic MET in cancer! We also use them to share usage information with our partners changes wont be saved until you sign up an. A long way off to providing innovative therapeutic solutions to address unmet medical needs globally Immunotherapy shown. 10.1158/0008-5472.Can-22-0770 Abstract Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer out to Biopharma! Using this site, you agree to our use of any information through the EurekAlert system ketoacidosis, collaborated. Is always on the lookout for new talent are registered trademarks of the U.S. Department of and... Options below to learn more about how you can get involved: 36066413 doi: 10.1007/s12094-019-02075-1 visit... Induced adenosine production, which is induced in MET-amplified EGFR-TKIresistant cells directly regarding opportunities...
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